229 research outputs found

    A Primer for Work-Based Learning: How to Make a Job the Basis for a College Education

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    Provides an overview of the Jobs to Careers model, in which employers and colleges collaborate to embed curricula and training in the work process, as a way to meet healthcare labor force needs. Includes grantee profiles, lessons learned, and worksheets

    Temporal integration in 17- and 20-month old infants as assessed by elicited imitation

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    The present study used a unique task derived from the elicited imitation paradigm to assess temporal integration in 17- and 20-month-old infants. Experiment 1 implemented a simpler task than has previously been used in order to tap temporal integration ability in 17-month-olds. The results indicated that the performance of 17- month-olds did not improve over that of previous research (de Haan & Bauer 1997). Experiment 2 added storage and processing demands to the de Haan and Bauer task in order to assess the robustness of temporal integration ability in 20-month-olds. The results indicated that the performance of 20-month-olds did not suffer with the added demands of the task. Implications of the findings in regards to the structure and development of working memory are discussed

    James Hainlen: An Oral History Of An Exemplary Public School Orchestra Director And His Program

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    Experts advise string teachers to identify and model successful string teachers and programs. However, there is a scarcity of literature that examines this subject. There is literature that examines exemplary band teachers and programs, and these works can be useful to the string teaching profession. However, string teachers ·can benefit more from literature that specifically examines exemplary string orchestra programs and teachers. The purpose of this study, therefore, was to gather information from a renowned public school string teacher about the components of his successful string orchestra program. The researcher conducted a personal interview with James Hainlen, retired director and chair of the Stillwater, Minnesota Public School\u27s orchestra program. The researcher questioned Hainlen on components of the Stillwater string program. Hainlen\u27 s comments from the interview are presented in chapter five of this paper. Many components of Hainlen\u27 s string program were like those discussed in existing literature pertaining to teaching band and orchestra. The researcher attributed the success of Hainlen\u27 s string program to a combination of his school politicking skills, a well-planned curriculum, a high standard for musical performance, accurate and thorough record keeping, special events planned for students, and the personal connections he made with students at all levels of the string program. These topics seem to be somewhat overlooked in the existing literature about string teaching

    Teaching the Standard Without Speaking the Standard: Variation Among Mandarin-Speaking Teachers in a Dual-Immersion School

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    In studies of nonstandard language in school settings, teachers are often characterized as speakers and promoters of the variety most valued by the school (Labov 1969, Wheeler & Swords 2006, etc.). When teachers\u27 native variety is not equivalent to the school variety, they are confronted with the challenge of constructing an educator persona in a linguistic market in which their speech may not be associated with education. This task is particularly daunting in a dual immersion classroom, where certain students are relying on the teacher as their primary source of a language they do not speak at home, and other students may be native speakers of a variety more standard than that spoken by the teacher. Evidence from the present study, examining the merger of retroflex and dental sibilant initials in Mandarin, indicates that teachers systematically employ more standard language in more “curricular” contexts, thus providing cues for students still developing their knowledge of language and social meaning

    Cardiac autonomic activity during sleep in high-altitude resident children compared with lowland residents

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    Study Objectives We aimed to characterize heart-rate variability (HRV) during sleep in Andean children native to high altitude (HA) compared with age, gender, and genetic ancestry-similar low-altitude (LA) children. We hypothesized that the hypoxic burden of sleep at HA could induce variation in HRV. As children have otherwise healthy cardiovascular systems, such alterations could provide early markers of later cardiovascular disease. Methods Twenty-six LA (14F) and 18 HA (8F) children underwent a single night of attended polysomnography. Sleep parameters and HRV indices were measured. Linear mixed models were used to assess HRV differences across sleep stage and altitude group. Results All children showed marked fluctuations in HRV parameters across sleep stages, with higher vagal activity during nonrapid eye movement sleep and greater variability of the heart rate during rapid eye movement (REM). Moreover, HA children showed higher very low-frequency HRV in REM sleep and, after adjusting for heart rate, higher low-to-high frequency ratio in REM sleep compared with children living at lower altitude. Conclusions We confirmed previous findings of a stage-dependent modulation of HRV in Andean children living at both HA and LA. Moreover, we showed subtle alteration of HRV in sleep in HA children, with intriguing differences in the very low-frequency domain during REM sleep. Whether these differences are the results of an adaptation to high-altitude living, or an indirect effect of differences in oxyhemoglobin saturation remains unclear, and further research is required to address these questions

    Formaldehyde Carcinogenicity Research: 30 Years and Counting for Mode of Action, Epidemiology, and Cancer Risk Assessment

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    Formaldehyde is a widely used high production chemical that is also released as a byproduct of combustion, off-gassing of various building products, and as a fixative for pathologists and embalmers. What is not often realized is that formaldehyde is also produced as a normal physiologic chemical in all living cells. In 1980, chronic inhalation of high concentrations of formaldehyde was shown to be carcinogenic, inducing a high incidence of nasal squamous cell carcinomas in rats. Some epidemiologic studies have also found increased numbers of nasopharyngeal carcinoma and leukemia in humans exposed to formaldehyde that resulted in formaldehyde being considered a Known Human Carcinogen. This article reviews the data for rodent and human carcinogenicity, early Mode of Action studies, more recent molecular studies of both endogenous and exogenous DNA adducts, and epigenetic studies. It goes on to demonstrate the power of these research studies to provide critical data to improve our ability to develop science-based cancer risk assessments, instead of default approaches. The complexity of constant physiologic exposure to a known carcinogen requires that new ways of thinking be incorporated into determinations of cancer risk assessment for formaldehyde, other endogenous carcinogens, and the role of background endogenous DNA damage and mutagenesis

    Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme

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    The APOE ε2/3/4 genotype has been associated with low-density lipoprotein cholesterol (LDL-C) and Alzheimer disease. However, evidence for associations with measures of cognitive performance in adults without dementia has been mixed, as it is for physical performance. Associations may also be evident in other genotypes implicated in LDL-C levels. As part of the Healthy Ageing across the Life Course (HALCyon) collaborative research programme, genotypic information was obtained for APOE ε2/3/4, rs515135 (APOB), rs2228671 (LDLR) and rs629301 (SORT1) from eight cohorts of adults aged between 44 and 90+years. We investigated associations with four measures of cognitive (word recall, phonemic fluency, semantic fluency and search speed) and physical capability (grip strength, get up and go/walk speed, timed chair rises and ability to balance) using meta-analyses. Overall, little evidence for associations between any of the genotypes and measures of cognitive capability was observed (e.g. pooled beta for APOE ε4 effect on semantic fluency z score=- 0.02; 95% CI=- 0.05 to 0.02; p value=0.3; n=18,796). However, there was borderline evidence within studies that negative effects of APOE ε4 on nonverbal ability measures become more apparent with age. Few genotypic associations were observed with physical capability measures. The findings from our large investigation of middle-aged to older adults in the general population suggest that effects of APOE on cognitive capability are at most modest and are domain- and age-specific, while APOE has little influence on physical capability. In addition, other LDL-C-related genotypes have little impact on these traits. © The Author(s) 2014

    University of Texas / M.D. Anderson Cancer Center Newsletter

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    Monthly report discussing cancer care and research to inform physicians
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